هیپر آلدوسترونیسم

[ستاره ی قطبی]

Persons with primary hyperaldosteronism have a problem with the adrenal gland that causes it to release too much aldosterone.

In secondary hyperaldosteronism, the excess aldosterone is caused by something outside the adrenal gland that mimics the primary condition.

Primary hyperaldosteronism used to be considered a rare condition, but some experts believe that it may be the cause of high blood pressure (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F000468.htm) in some patients. Most cases of primary hyperaldosteronism are caused by a noncancerous (benign) tumor of the adrenal gland. The condition is common in people ages 30 - 50.

Secondary hyperaldosteronism is generally related to high blood pressure. It is also related to disorders such as:


Cirrhosis (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F000255.htm) of the liver
Heart failure (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F000158.htm)
Nephrotic syndrome (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F000490.htm)

refrence (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F000330.htm)

[ستاره ی قطبی]

هیپر آلدوسترونیسم اولیه که یکی از بیماری های اندام فوق کلیه محسوب میشود به علت ترشح زیاد هورمون آلدوسترون در شخص ایجاد میشود.
هیپر آلدوسترونیسم ثانویه،آلدوسترون اضافی توسط یک عامل خارجی ایجاد می شود که همان علائم اولیه را تقلید میکند.
هیپر آلدوسترونیسم اولیه قبلا به عنوان بیماری با عوارض نادر بررسی میشد اما اکنون عوارضی از جمله فشار خون بالا در بعضی بیماران مشاهده گردیده است.
بیشتر موارد هیپر آلدوسترونیسم اولیه توسط سلول های غیر سرطانی فوق کلیه ایجاد می شود.این شرایط بیشتر در سنین بین 30-50 در افراد رخ می دهد.

هیپرآلدوسترونیسم ثانویه عموما با فشار خون بالا مرتبط است و همچنین با بیماریهای زیر ارتباط دارد:
سیروز کبدی
سکته قلبی
سندروم نفروتیک

[ستاره ی قطبی]

symptoms



Fatigue (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F003088.htm)
Headache (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F003024.htm)
High blood pressure
Intermittent paralysis (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F003190.htm)
Muscle weakness (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F003174.htm)
Numbness (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F003206.htm)

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نشانه ها


خستگی و فرسودگی
سر درد
فشار خون بالا
فلج متناوب
ضعف ماهیچه
از دست دادن حس

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Exams and Tests


Abdominal CT scan (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F003789.htm)
ECG (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F003868.htm)
Plasma aldosterone (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F003704.htm) level
Plasma renin activity (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F003698.htm)
Serum potassium (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F003484.htm) level
Urinary aldosterone (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F003621.htm)

Occasionally, it is necessary to insert a catheter into the veins of the adrenal glands to determine which of the adrenals contains the growth.

This disease may also affect the results of the following tests:
CO2 (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F003469.htm)
Serum magnesium (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F003487.htm)
Serum sodium (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F003481.htm)
Urine potassium (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F003600.htm)
Urine sodium (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F003599.htm)

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Cirrhosis



liver disease (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F000205.htm).





Causes


Cirrhosis is caused by chronic liver disease. Common causes of chronic liver disease in the United States include:




Hepatitis C (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F000284.htm)
infectionLong-term alcohol abuse (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F001944.htm) (see alcoholic liver disease (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F000281.htm))




Other causes of cirrhosis include:
Autoimmune inflammation of the liver (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F000245.htm)
Disorders of the drainage system of the liver (the biliary system), such as primary biliary cirrhosis (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F000282.htm) and primary sclerosing cholangitis (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F000285.htm)Hepatiti s B (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F000279.htm)Medicati onsMetabolic disorders of iron and copper (hemochromatosis (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F000327.htm) and Wilson's disease (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F000785.htm))Nonalco holic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH)

Symptoms
Symptoms may develop gradually, or there may be no symptoms.
When symptoms do occur, they can include





Abdominal indigestion (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F003260.htm) or pain
Confusion (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F003205.htm) or problems thinking
Impotence (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F003164.htm), loss of interest in ***, and breast development (gynecomastia (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F003165.htm)) in men
Nausea (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F003117.htm) and vomiting
Nosebleeds or bleeding gums
Pale or clay-colored stools
Small, red spider-like blood vessels on the skin
Swelling or fluid buildup of the legs (edema (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F003103.htm)) and in the abdomen (ascites (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F000286.htm))
Vomiting blood (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F003118.htm) or blood in stools
Weakness
Weight loss
Yellow color in the skin, mucus membranes, or eyes (jaundice (http://njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.nlm.nih.gov%2F medlineplus%2Fency%2Farticle%2F003243.htm) Cirrhosis is scarring of the liver and poor liver function as a result of chronic

[ستاره ی قطبی]

سیروز کبدی

سیروز کبدی که در نتیجه ی بیماری های مضمن کبدی ایجاد میشود عملکرد آن را مختل می کند.



علائم

شایع ترین بیماری های کبدی در آمریکا از قرار زیر است:




هپاتیت c در اثر مصرف طولانی مدت مشروبات الکلی

از دیگر علائم:




التهاب خود ایمنی کبدی
بی نظمی در سیستم ترشح صفراوی
سیروز صفراوی اولیه و التهاب رگ های صفراوی
هپاتیتB
اخلالات متابولیکی آهن و مس
بیماری کبد چرب غیر الکلی




علائم ممکن است به تدریج پیشرفت کنند. ممکن است علائم مشاهده نشوند.





دیر هضمی یا درد های شکمی

کاهش هوشیاری و اختلالات فکری
ناتوانی جنسی و کاهش میل جنسی

بزرگ شدن غدد پستانی در آقایان
حالت تهوع و استفراغ

بیرنگ شدن مقعد و ؟
شبکه های عنکبوتی رگ های خونی روی پوست
ادم پا و شکم

ضعف
کاهش وزن
زرد شدن چهره یا چشم ها(زردی یا یرقان)

[ستاره ی قطبی]

Causes of Primary Hyperaldosteronism (Diseases Database):

The follow list shows some of the possible medical causes of Primary Hyperaldosteronism (http://www.njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.wrongdiagnosis .com%2Fp%2Fprimary_hyperaldosteronism%2Fintro.htm) that are listed by the Diseases Database
Adrenal cortex tumours (http://www.njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.wrongdiagnosis .com%2Fmedical%2Fadrenal_cortex_tumours.htm)
Hypokalaemic distal renal tubular acidosis (http://www.njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.wrongdiagnosis .com%2Fmedical%2Fhypokalaemic_distal_renal_tubular _acidosis.htm)
Juxtaglomerular cell tumor (http://www.njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.wrongdiagnosis .com%2Fmedical%2Fjuxtaglomerular_cell_tumor.htm)
Hepatic failure (http://www.njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.wrongdiagnosis .com%2Fl%2Fliver_failure%2Fintro.htm)
Fludrocortisone (http://www.njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.wrongdiagnosis .com%2Fmedical%2Ffludrocortisone.htm)
Nephrotic syndrome (http://www.njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.wrongdiagnosis .com%2Fn%2Fnephrotic_syndrome%2Fintro.htm)
Malignant hypertension (http://www.njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.wrongdiagnosis .com%2Fm%2Fmalignant_hypertension%2Fintro.htm)
C11-Hydroxylase deficiency (http://www.njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.wrongdiagnosis .com%2Fmedical%2Fc11_hydroxylase_deficiency.htm)
Bartter's syndrome (http://www.njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.wrongdiagnosis .com%2Fb%2Fbartter_syndrome%2Fintro.htm)
Glycyrrhizic acid (http://www.njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.wrongdiagnosis .com%2Fmedical%2Fglycyrrhizic_acid.htm)
Dilated cardiomyopathy (http://www.njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.wrongdiagnosis .com%2Fd%2Fdilated_cardiomyopathy%2Fintro.htm)
Hemangiopericytoma (http://www.njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.wrongdiagnosis .com%2Fh%2Fhemangiopericytoma%2Fintro.htm)
Chloridorrhea, hereditary (http://www.njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.wrongdiagnosis .com%2Fmedical%2Fchloridorrhea_hereditary.htm)
Aldosterone (http://www.njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.wrongdiagnosis .com%2Forgan%2Faldosterone.htm)
C17-hydroxylase deficiency (http://www.njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.wrongdiagnosis .com%2Fmedical%2Fc17_hydroxylase_deficiency.htm)

Glucocorticoid-suppressible hyperaldosteronism (http://www.njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.wrongdiagnosis .com%2Fmedical%2Fglucocorticoid_suppressible_hyper aldosteronism.htm)


Read more at http://www.wrongdiagnosis.com/p/primary_hyperaldosteronism/causes.htm?ktrack=kcplink (http://www.njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.wrongdiagnosis .com%2Fp%2Fprimary_hyperaldosteronism%2Fcauses.htm %3Fktrack%3Dkcplink)

[ستاره ی قطبی]

علل های احتمالی ایجاد هایپرالدوسترونیسم

نقص آنزیمی C17 وC11هیدروکسیلاز

تومورهای بخش قشری فوق کلیه

فشارخون بالا در اثر مشکلات کلیوی (باریکی رگ های کلیه و ..)

سنروم بتر(بیماری نادر ژنتیکی که از خصوصیات آن کاهش اسیدیته ی خون و کاهش پتایسم میباشد)

فلودروکورتیزون(مینرالوکور� �یکوئید سنتزی بااثرات ضد التهابی)

Glycyrrhizic acid (http://www.njavan.com/forum/redirector.php?url=http%3A%2F%2Fwww.wrongdiagnosis .com%2Fmedical%2Fglycyrrhizic_acid.htm) با اثرات ضد التهابی و مهار 11بتا هیدروکسی استروئیددهیدروژناز

Dilated cardiomyopathy (کشیدگی فیبرهای عضله ی قلبی در اثر انقباض ناصحیح بطنها )

Hemangiopericytom (http://www.njavan.com/forum/redirector.php?url=http%3A%2F%2Fwrongdiagnosis.pub s.righthealth.com%2Ftopic%2FHemangiopericytoma%3Fa s%3Dclinks%26ac%3D1425%26afc%3D2168586466%26p%3Dcl 1)a (http://www.njavan.com/forum/redirector.php?url=http%3A%2F%2Fwrongdiagnosis.pub s.righthealth.com%2Ftopic%2FHemangiopericytoma%3Fa s%3Dclinks%26ac%3D1425%26afc%3D2168586466%26p%3Dcl 1):تومور کند پیش رونده در قسمتهای عمقی بافت نرم به خصوص در ناحیه شکم،لگن،شانه،بازو و ران)